Dr. Mandar Deshpande

AREA(S) OF INTEREST:

Robotic assisted Surgeries, Head and Neck Cancer Surgeries, Head & Neck Onco Surgery, Trans Oral Robotic Surgeries (TORS), Laser surgeries (Laryngeal & Oral) Conservative, Laryngeal Surgeries, Minimally invasive Parathyroidectomy and Thyroidectomies for Benign and Malignant cases

TREATMENTS/PROCEDURES OFFERED:

Diagnostic procedures (Scopy and Biopsy),, Counseling for cancer patients,, Treatment, planning and execution (surgery/chemotherapy/radiotherapy)., Palliative care for terminal stage patients.

NAME OF INSTITUTE(S):

• MBBS, LTM Medical College, Sion, Mumbai
• MS, DNB(Surgical Oncology), Tata Memorial Hospital
• Head & Neck Robotic Surgery, Severance Hospital, Yonsei University, South Korea

• Paper titled ‘Analysing reasons for non-enrolment on clinical trial. Are developing countries different from developed ones? ‘was awarded ‘Best Paper Award’ at ‘7thAmerican Head and Neck society meeting’ at San Francisco, USA. It was selected from 1200 papers from 57 countries.
• Best paper awards 5 national conferences.
• Best Video Award at 3 national conferences

Worked at one of the most prestigious cancer centres in the world, Tata Memorial Hospital for 13 years. Advanced training in Robotic Head and Neck surgery (Korea). Currently working as a Consultant of Head and Neck Services in KDAH since 11 years now.

KDAH Experience :

He has performed more than 5000 head and neck surgeries at Kokilaben Hospital so far. This includes the first Trans Oral Robotic Surgery for Oro-pharyngeal tumour in Mumbai. He is the first surgeon in the country to do Robotic assisted Neck dissections and Trans Oral Robotic surgeries. He also specializes in Conservative Laryngectomy with minimal morbidity, Treatment of thyroid tumours both benign and malignant, Minimally invasive Parathyroidectomies especially for Geriatric patients with co-morbidities.

He was Assistant Professor and then Associate Professor of Head & Neck Oncology at Tata Memorial Hospital for 7 years from 2002 to 2009.

• Speaker at various National and International conferences, Authored chapters in es-teemed academic textbooks. Winner of the best poster in an International Oncology Conference held in USA.
• Dr. Mandar Deshpande has 61 publications in Indexed Journals.
• Dr. Mandar Deshpande - One of the few Surgeons in the country to perform Robotic Assisted Neck dissections through minimal incision in the neck.

Publications

• Robotic Retroauricular Thyroidectomy: initial experience from India.Krishnakumar Thankappan, Surendar Dabas, Mandar Deshpande. Gland Surgery 2017 Vol 6 No.3
• Robotic Assisted Neck Dissection. Kalyan Chakradhar, Mandar Deshpande, Rishi Khosa. October 2016
• Nimotuzumab and Intensity Modulated Radiation Therapy(IMRT) in the Concurrent setting of Locally Advanced Head and Neck Cancers: early Results of a prospective trial in India. Kaustav Talapatra, Sandeep Goyle, Mandar Deshpande. International Journal of radiation Oncology October 2016.
• Phase III randomised trial of surgery followed by conventional radiotherapy (5fr/wk) (Arm A) Vs Concurrent Chemo-radiotherapy (arm B) Vs accelerated radiotherapy (6 fr/wk) (Arm C) in Locally Advanced, Stage III and IV , resectable, squamous cell carcinoma of oral cavity - Oral Cavity Adjuvant Therapy Trial (OCAT) Final Result. Sarbani Ghosh, Devendra Chaukar, Mandar Deshpande, Anil D’Cruz. Journal of Clinical Oncology May 2016.
• Cell- Free Epstein Barr Virus -DNA in patients with nasopharyngeal carcinoma. Manju Senger, Jyoti Kode, Kamini Jadhav, Mandar Deshpande Head Neck December 2015.
• Guidelines for management of recurrent or metastatic head and neck cancer. P Parikh, K. Prabhash, M. Deshpande, J.P. Agarwal. Indian Journal of CancerApril 2014.
• Prospective analysis of analysis of reasons for non-enrolment in a phase III randomised controlled trial. Vedang Murthy, Kasturi Awatagiri, Mandar Deshpande, J. P. AgarwalJournal of Cancer Research and Therapeutics. Jan 2012.
• Clinical Localization of the spasmodic segment in voice limiting pharyngoesophageal spasm. Mandar Deshpande, Vishal Rao, Pankaj Chaturvedi, Anil D’Cruz. International Journal of Head and Neck Surgery Sept 2010
• Prosthetic Voice Rehabilitation after total laryngectomy. Mandar Deshpande. Indian Journal of Surgical Oncology. April 2010.
• Temporal Bone Malignancies and modifications of the surgical methods. Deepa Nair, Prathamesh Pai, Ali Asgar, Mandar Deshpande, Anil D’Cruz. Skull Base surgery. Oct 2009.
• Factors influencing prognosis in squamous cell carcinoma of tongue: Retrospective analysis of Major Glossectomy Oral Oncology July 2009 D. Chaukar, P. Pai, M. Deshpande, G. Pantvaidya, A.K. D’Cruz.
• Masseter flap and Tongue flap as an alternative to free radial forearm flap for reconstruction of the mucosal defects following excision of buccal mucosa cancers. S.K. Panwar. Pankaj Chaturvedi, Prathamesh Pai, Mandar Deshpande, Anil D’Cruz. International Journal of Oral and Maxillofacial surgery. May 2009.
• Prognostic factors for loco-regional failure in early stage (I and II) squamous cell carcinoma of the gingivobuccal complex. Walvekar RR, Chaukar DA, Deshpande MS, Pai PS, Chaturvedi P, Kakade AC, D'Cruz AK. Eur Arch Otorhinolaryngol.  2010 Jan 12.
• Squamous cell carcinoma of base of tongue in a patient with Fanconi's anemia treated with radiation therapy: Case report and review of literature. Budrukkar A, Shahid T, Murthy V, Hussain T, Mulherkar R, Vundinti BR, Deshpande M, Sengar M, Ghosh-Laskar S, Agarwal JP. Head Neck. 2009 Aug 11.
• Validation and assessment of voice-related quality of life in Indian patients undergoing total laryngectomy and primary tracheoesophageal puncture. Deshpande MS, Kakade AC, Chaukar DA, Gore VT, Pai PS, Chaturvedi P, D'Cruz AK. Head Neck. 2009 Jan;31(1):37-44.
• PET-CT in recurrent head neck cancers: a study to evaluate impact on patient management. Pantvaidya GH, Agarwal JP, Deshpande MS, Rangarajan V, Singh V, Kakade A, D'Cruz AK.J Surg Oncol. 2009 Oct 1;100(5):401-3.
• Does Diagnostic Lignocaine Block Have a Therapeutic Value in Treatment of Hypertonic Pharyngoesophageal Segment? Desphande M, Rao V, Chaukar D, Chaturvedi P, Pai P, D'cruz A.Laryngoscope. 2008 Apr 24. [Epub ahead of print]
• Clinical localization of Hypertonic Pharyngo-esophageal segment. Accepted for publication in World Journal of Surgical Oncology. Deshpande M, Rao V, Chaukar D, Chaturvedi P, Pai P, D'cruz A.
• Percutaneous Endoscopic Gastrostomy site metastasis in Head and neck cancers  – Utility of FDG – PET - CT. Nilendu C. Purandare, Venkatesh Rangarajan, Anshu Rajneesh Sharma, Sneha Shah, Natasha Singh, Abhishek Arora, Sujata Pathak, Mandar Deshpande. Diagnostic and Interventional Radiology. 2008;14: 88 – 93.
• Squamous cell carcinoma of the gingivobuccal complex: predictors of locoregional failure in stage III-IV cancers. Walvekar RR, Chaukar DA, Deshpande MS, Pai PS, Chaturvedi P, Kakade A, D'Cruz AK. Oral Oncol. 2009 Feb;45(2):135-40. Epub 2008 Jul 14.
• Quality of life in head and neck cancer survivors: a cross-sectional survey. Chaukar DA, Walvekar RR, Das AK, Deshpande MS, Pai PS, Chaturvedi P, Kakade A, D'Cruz AK. Am J Otolaryngol. 2009 May-Jun;30(3):176-80. Epub 2008 Oct 1.
• Elective neck dissection for the management of the N0 neck in early cancer of the oral tongue: need for a randomized controlled trial. D'Cruz AK, Siddachari RC, Walvekar RR, Pantvaidya GH, Chaukar DA, Deshpande MS, Pai PS, Chaturvedi P.Head Neck. 2009 May;31(5):618-24.
• Cancer of the buccal mucosa: a tale of two continents. Pathak KA, Nason R, Talole S, Abdoh A, Pai P, Deshpande M, Chaturvedi P, Chaukar D, D'Cruz A, Bhalavat R. Int J Oral Maxillofac Surg. 2009 Feb;38(2):146-50.
• Verrucous carcinoma of the oral cavity: A clinical and pathological study of 101 cases. Walvekar RR, Chaukar DA, Deshpande MS, Pai PS, Chaturvedi P, Kakade A, Kane SV, D'Cruz AK. Oral Oncol. 2009 Jan;45(1):47-51.
• Radiology quiz case 2. Pseudoaneurysm of the facial artery.Kamath A, Nagarajan G, Kulkarni AV, Kulkarni S, Deshpande MS,D'Cruz A. Arch Otolaryngol Head Neck Surg. 2008 Apr; 134 (4):443, 445.
• In vitro chemosensitivity profile of oral squamous cell cancer and its correlation with clinical response to chemotherapy. KA Pathak, AS Juvekar, DK Radhakrishnan, MS Deshpande, VR Pai, P Chaturvedi, PS Pai, DA Chaukar, AK D'Cruz, PM Parikh Indian J Cancer. 2007 Oct-Dec; 44 (4):142-6.
• Malignant pilar tumor of the scalp: a case report and review of literature. J Cancer Res Ther. Manish Siddha, Ashwini Budrukkar, Tanuja Shet, Mandar Deshpande, Ayan Basu, Nikhilesh Patil, Rajendra Bhalavat 2007 Oct-Dec;3(4):240-3.
• Extensive tubercular neck lymphadenopathy in a man with early-stage tongue cancer. Chaturvedi P, Pai PS, Chaukar DA, Deshpande MS,Rangarajan V, Purandare N, D'cruz AK. Nat Clin Pract Oncol. 2007 Dec; 4 (12):726-8.
• Squamous cell carcinoma of the superior gingival-buccal complex. Pathak KA, Mathur N, Talole S, Deshpande MS, Chaturvedi P, Pai PS, Chaukar DA, D'Cruz AK. Oral Oncol. 2007 Sep; 43(8):774-9. Epub 2007 Feb 15.
• A prospective study of pharyngocutaneous fistulas following total laryngectomy. SS Qureshi, P Chaturvedi, PS Pai, DA Chaukar, MS Deshpande, KA Pathak, AK D'cruz J Cancer Res Ther. 2005 Jan-Mar; 1 (1):51-6.
• Clinical and statistical aspects of P value and confidence interval. MS Deshpande, Anagha C. Kakade. Mammology 2006 2 (1) 27-32.
• Buccal plate excision for buccal paramandibular spread. Kumar Alok Pathak, , Mandar S. Deshpande, Navneet Mathur, Amit S. Date, Pankaj Chaturvedi, Prathamesh S. Pai, Devendra A. Chaukar, Anil K. D'Cruz J Surg Oncol. 2006 Sep 1; 94 (3):257-9.
• Selective neck dissection (I-III) for node negative and node positive necks.Kumar Alok Pathak, Das Ashok, K.Agarwal Ritu,Talole Sanjay,Deshpande Mandar, Chaturvedi Pankaj, Pai Prathamesh ,Chaukar Devendra A,   D'cruz Anil K.Oral Oncol. 2006 Sep; 42 (8):837-41. Epub 2006 May 26.
• Factors affecting immediate post-operative outcomes in surgically treated patients of oral cancers. April 2005 Oral Oncology Mandar Deshpande, D.A> Chaukar. A.K. D’Cruz
• Primary reconstruction of small mandibular defects by using mandibular remnant. Kumar Alok Pathak, Bhavin C. Shah,  Amit S. Date,  Mandar S. Deshpande,  Pankaj Chaturvedi, Prathamesh S. Pai, Devendra A. Chaukar, Anil K. D'Cruz,  J Surg Oncol. 2006 Jun 1; 93 (7):593-5. 
• Quality of life of head and neck cancer patient: validation of the European organization for research and treatment of cancer QLQ-C30 and European organization for research and treatment of cancer QLQ-H&N 35 in Indian patients.DA Chaukar, AK Das, MS Deshpande, PS Pai, KA Pathak, P Chaturvedi, AC Kakade, RW Hawaldar, AK DCruz
  Indian J Cancer. 2005 Oct-Dec; 42 (4):178-84.
• Split therapy: planned neck dissection followed by definitive radiotherapy for a T1, T2 pharyngolaryngeal primary cancer with operable N2, N3 nodal metastases—a prospective study. A.K. D'cruz, G.H. Pantvaidya, J.P. Agarwal, MD , D.A. Chaukar, K.A. Pathak, M.S. Deshpande, P.S. Pai, P. Chaturvedi, K.A. Dinshaw, J Surg Oncol. 2006 Jan 1; 93 (1):56-61.
• Simultaneous reconstruction of large skin and mucosal defect following head and neck surgery with a single skin paddle pectoralis major myocutaneous flap. P Chaturvedi, P S Pai, K A Pathak, D A Chaukar,M S Deshpande, A K D’cruz, J Laryngol Otol. 2005 Apr;119(4):303-5.
• Advanced squamous cell carcinoma of lower gingivobuccal complex: patterns of spread and failure. Kumar Alok Pathak, Samir Gupta,Sanjay Talole, Vishal Khanna, Pankaj Chaturvedi, Mandar S. Deshpande, Prathamesh S. Pai, Devendra A. Chaukar,  Anil K. D'Cruz, Head Neck. 2005 Jul; 27 (7):597-602.
• Supra-Omohyoid Neck Dissection: 8 years  Institutional Experience. Oral Oncology April 2005, Kumar Alok Pathak, Mandar Deshpande, Anil D’Cruz.
• Marginal Mandibulectomy for Gingivo-Buccal Complex cancers. Oral Oncology 2005. Mandar Deshpande, Kumar Alok Pathak, Anil K D’Cruz.
• Pathological fracture in a pregnant woman. Chaturvedi P, Puri A, Agarwal MG, Pai PS, Pathak KA, Chaukar DA, Deshpande MS,Decruz AK. Postgrad Med J. 2004 Dec; 80 (950):740, 743.
• Upfront submandibular salivary gland transfer in pharyngeal cancers. Pathak KA, Bhalavat RL, Mistry RC, Deshpande MS, Bhalla V, Desai SB, Malpani BL. Oral Oncol. 2004 Oct; 40 (9):960-3.
• Marginal mandibulectomy for lateral sulcus tumours. Pathak KA, Agarwal R, Deshpande MS. Eur J Surg Oncol. 2004 Sep; 30 (7):804-6.
• A novel technique of raising a pectoralis major myocutaneous flap through the skin paddle incision alone. Pankaj Chaturvedi, Kumar A. Pathak, Pathamesh S. Pai, Devendra A. Chaukar, Mandar S. Deshpande, Anil K. D'Cruz.J Surg Oncol. 2004 May 1; 86 (2):105-6.
• Reconstruction of early lower gingivo buccal complex lesions using floor of mouth advancement augmented with hyoglossus release. Prathamesh S. Pai, Pankaj Chaturvedi, Anil K. D'Cruz,Devendra A. Chaukar,  Kumar Alok Pathak, Mandar S. Deshpande, Dilip K. Kar, . J Surg Oncol. 2004 Apr 1; 86 (1):41-3.
• Para-sternal approach for pectoralis major myocutaneous flap in females. Pankaj Chaturvedi, Prathamesh S. PAI, Kumar A. Pathak, Devendra A. Chaukar, Mandar S. Deshpande, Anil K. D’cruz J Surg Oncol. 2004 Mar 15; 85 (4):199-201.
• Extra-oral knotting of tie-over sutures: a novel technique to bolster the split thickness skin graft for a buccal mucosal defect. Pankaj Chaturvedi, Prathamesh S. Pai, Anil K. D’cruz, Kumar A. Pathak, Devendra A. Chaukar, Mandar S. Deshpande, Shishir Shetty .J Surg Oncol. 2003 Oct;84 (2):103-4.
• Thoracic duct cyst of the mediastinum. C S Pramesh, Mandar S Deshpande, Gouri H Pantvaidya, Sanjay Sharma, and Ramakant K Deshpande, .Ann Thorac Cardiovasc Surg. 2003 Aug;9(4):264-5.
• Small cell carcinoma of the esophagus: the Tata Memorial Hospital experience. Gouri H. Pantvaidya, C.S. Pramesh, Mandar S. Deshpande, Nirmala A. Jambhekar, Sanjay Sharma, Ramakant K. Deshpande,Ann Thorac Surg. 2002 Dec;74(6):1924-7.
• Metastatic adenocarcinoma in testis presenting as a testicular mass--a case report and review of literature. Deshpande MS, Kulkarni JN. Can J Urol. 2003 Feb;10 (1):1770-1.
• Core needle biopsy for bone tumours. Pramesh C. S., Deshpande M. S., Pardiwala D. N., Agarwal M. G. and Puri A. Eur J Surg Oncol. 2001 Nov;27 (7):668-71.

Professional Memberships

• AHNS (American Head Neck Society)
• FHNO (Foundation of Head & Neck Oncology)
• ISO (Indian Society of Oncology)
• IASO ( Indian Association of Surgical Oncology

Dr. Mandar Deshpande - The Da Vinci Robotic System

Case I:
PARAPHARYNGEAL SPACE TUMOR
A young patient presented with a tumor around his pharynx (the passage that leads from the cavities of the nose to voice box and food pipe). The surgery is usually done through a cut in the neck. The patient was specifically concerned about the scar and damage to his facial nerve which can have devastating consequences like facial disfigurement. With the help of the DA VINCI robotic system, the incision in the neck was avoided and tumor was removed completely through his mouth with no resulting scars or nerve damage.

Case II:
TONSILLAR SARCOMA (A RARE MALIGNANT TUMOR OF THE TONSIL)
A patient presented with growth on the Tonsils diagnosed as sarcoma. This is an area very prone to bleeding and pain after surgery. Also patients may have difficulty in swallowing food because of a raw spot in the mouth. With the DA VINCI system, the tumor was removed radically and all the complications were minimized. Healing of the oral wound was faster and patient could resume swallowing quicker resulting in adequate nutrition which in turn accelerates healing.

Case III:
LARGE MINOR SALIVARY GLAND TUMOR ON BASE OF TONGUE
TRANS ORAL ROBOTIC SURGERY (TORS) is the state of the art, minimally invasive surgical technique for small tumors on the base of tongue, with the optical and technical advantages of robotic surgical instruments; we were able to remove a large tumor with adequate margins. The system provided excellent visualization of the posterior part of the tongue, not easily achievable with conventional surgery with good bleeding control and excellent post operative outcomes.

Case IV:
NECK DISSECTION FOR ORAL CANCERS
The first ever Robotic Neck Dissection in INDIA was performed at our hospital.In this procedure a small cut was made at the back of ear and with the help of Robotic arms the entire neck could be visualized and approached. In conventional surgery this requires large cuts in front of neck which results in disfiguring scars. Now with the advent of DA VINCI system this has been overcome and surgery could be completed with cosmetically appealing scars and excellent post operative outcome. The duration of hospital stay is also reduced due to faster recovery and early return to normalcy.