Dr. Annu Aggarwal

AREA(S) OF INTEREST:

Cognitive and Behavioural Neurology, Memory Disorders, Wilson Disease, Neurodegenerative Diseases, Vascular dementia, Critical neurology

PROCEDURES PERFORMED:

Diagnosis, treatment, rehabilitation (physical and cognitive) and, education and counselling services for patients and their caregivers, Dementias such as Alzheimer disease and Fronto-Temporal Dementias (FTDs). , Neurodegenerative dementias including Parkinson disease Dementia (PDD), Corticobasal Syndrome (CBS), Diffuse Lewy Body Disease (DLB), Progressive Supranuclear Palsy (PSP), Neuroacanthocytosis (NAC), Huntington disease, Vascular dementia following stroke or hypoxic-brain injury, Creutzfeldt-Jakob disease(CJD, mad cow or prion disease)and other rapidly progressive dementias, Normal pressure hydrocephalous (NPH), Antibody-mediated dementias, Stroke, Critical care neurology, Movement disorders, Metal deposition disorders in the brain, such as Wilson Disease, Brain Iron Accumulation Disorders (NBIA), Brain Manganese Accumulation Disorders (AHLD), Brain Calcium Accumulation Disorders, Multiple sclerosis (MS) and other demyelinating diseases like Neuromyelitis Optica (NMO) and Acute Dissminated Encephalomyelitis (ADEM), Gait disorders, Neurogenetic disorders, Autoimmune neurological disorders, such as Limbic Encephalitis, Vasculitis, Myasthenia Gravis, Autoimmune Neuropathy (AIDP, GBS), Brain infections

NAME OF INSTITUTE(S):

• MRCP(UK), Royal College of Physicians of London, UK
• Diplomate of National Board, Neurology, Department of Neurology, Jaslok Hospital and Medical Research Centre, Mumbai, India National Board of Examinations, Government of India, New Delhi, India
• Intensive Care Medicine, PD Hinduja Hospital & Medical Research Centre, Mumbai, India
• MD Internal Medicine, BYL Nair Charitable Hospital and Topiwala National Medical College, Mumbai, India, University of Mumbai, Mumbai, India
• MBBS, Lokmanya Tilak Municipal General Hospital, Mumbai, India, Lokmanya Tilak Municipal General Hospital, University of Mumbai, Mumbai, India

FELLOWSHIPS:

• Cognitive and Behavioural Neurology, Department of Neurology, Royal Adelaide Hospital, Adelaide, Australia
• Cognitive and Behavioural Neurology, University Department of Medicine, University of Adelaide, Adelaide, Australia
• Movement Disorders, Movement Disorders Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, India

• The Diplomate of the National Board (Neurology) from the NBE, New Delhi
• The Membership of the Royal College of Physicians of UK (MRCP (UK)) by the Royal College of London
• Second Best Paper award, APICON Conference 2017 at the 72nd Annual conference of the Association of Physicians of India (APICON), Mumbai, India for, Patil L, Sorathiya P, Munshi M, Sanghvi D, Mani J, Kulkarni N, Bhatt M, Singhal T, Aggarwal A, \Listeria monocytogens infection in a tertiary care center from 2009-2016: Incidence, clinical features and outcomes."
• Best Paper Award, BNA Meet Oct 2016 At the Bombay Neurosciences Association meet for “Patil L, Shetty NR, Shaikh J, Doshi B, Aggarwal A, \Acute ascending accid quadriparesis in a 55 year man."
• Blue Ribbon Highlights, MDS Congress 2015 at the 19th International Congress of Parkinson's Disease and Movement Disorders, San Diego,USA for, “Chandhok G, Horvath J, Aggarwal A, Bhatt M, Zibert A, Schmidt H.H.J, “Drug response to zinc and D-penicillamine in ATP7B mutant hepatic cell lines"
• Blue Ribbon Highlights, MDS Congress 2015 at the 19th International Congress of Parkinson's Disease and Movement Disorders, San Diego, USA, for “Chandhok G, Sauer V, Aggarwal A, Bhatt M, Zibert A, Schmidt H.H.J, Establishment and validation of the _rst stable human ATP7B knockout hepatoma cell line: A Wilson disease cell
• model"
• Best Paper, IAN Conference 2013 at the 21st Annual Indian Academy of Neurology Conference, Indore, India, for
• “Chhabria MA, Bhatt M, Balasubramanium A, Aggarwal A, \Deep Brain Stimulation in Neuroacanthocytosis and Tardive Dyskinesia."
• Shortlisted for Best Paper, AARS Meet 2013 at the 113th Annual Meeting of the American Roentgen Ray Society (ARRS), Washington DC, USA, for, “Munshi M, Aggarwal A, Sanghvi D, Ravan A, Parekh S, Bhatt M, \Correlation of brain MRI abnormalities in Wilson disease with clinical disability"
• Best paper award, International Dystonia Symposium 2011 at the 5th International Dystonia Symposium, Barcelona, Spain for, “Schneider S, Aggarwal A, et al, \Indian-subcontinent NBIA: Unusual phenotypes, novel PANK2 mutations, and undetermined genetic forms"
• Dr Jane Page Research Fellowship 2008-09 for training in Cognitive and Behavioural Neurology, Department of Neurology, Royal Adelaide Hospital, Adelaide, Australia
• Hargobind Foundation Medical Fellowship 2008-09 for training in Cognitive and Behavioural Neurology
• Postdoctoral Fellowship in Movement Disorders 2005-08 at Jaslok Hospital and Medical Research Centre, supported in part by Parkinson's Disease Foundation of India

Dr.Aggarwal graduated with an MBBS from LTM Medical College, Mumbai and obtained her postgraduate degree in Internal Medicine from TN Medical College, Mumbai. She worked as Intensive Care Unit Associate at Hinduja Hospital before joining Jaslok Hospital and Research Centre, Mumbai. There she specialised in neurology and was awarded the Diplomate of the National Board (Neurology) from the NBE, New Delhi. Recently she was awarded the Membership of the Royal College of Physicians of UK (MRCP (UK)) by the Royal College of London.

After being awarded DNB (Neurology) Dr Aggarwal continued at Jaslok Hospital as a postdoctoral fellow, and developed a new paradigm to diagnose and treat people with Wilsons Disease, including a clinical scale to assess disease progression and treatment response. Her other work during this period involved the management of neurological diseases resulting from liver failure and iron deposition in the brain, and an epidemiological study of Parkinsons Disease among Parsees residing in Mumbai.

In 2008-09, Dr. Aggarwal was a postdoctoral fellow in cognitive and behavioural neurology at the Royal Adelaide Hospital (RAH), Adelaide. She was also affiliated with the University of Adelaide, Department of Medicine and the South Australian brain rehabilitation services at the Hampstead Rehabilitation Centre. At RAH she studied the problems of hallucinations in people with Parkinsons Disease, violent behaviours in sleep (REM behaviour disorders), memory impairment, problems of mobility in patients with Downs Syndrome, and respiratory problems in people with neurodegenerative diseases.

KDAH Experience

Dr Annu Aggarwal is a senior consultant neurologist at KDAH, where she deals with brain and nervous system disorders. These can be genetic or arise due to brain injuries, infections or degeneration; they can strike suddenly or develop slowly over time; and can manifest themselves not only as cognitive problems but also with impairment in vision, gait or even behaviour. Therefore, early and accurate diagnosis and intervention are essential for recovery. Dr Aggarwal with her 25 years of experience in medicine, aided by state-of-the-art laboratory, neuroimaging, surgical and rehabilitative resources available at KDAH, is dedicated to providing the best of care to patients with neurological ailments.

Dr Aggarwal specializes in caring for people with cognitive, behavioural, and memory problems. Such problems can develop with aging, as a result of neurodegenerative dementias, and are increasingly common with an ageing population. They can also be seen in younger patients due to neuro-metabolic disorders such as Wilson disease, epilepsy, neurodegeneration or other. Dr Aggarwal is at the forefront both in treating patients with such disorders, and in developing better diagnosis and treatment strategies for improving their care

Beside her clinical work, Dr Aggarwal maintains an active research program that benefits both her patients and the wider medical field. She has won several awards for her academic and research work, including the highly competitive Hargobind Foundation Scholarship, Dr Jane Page Scholarship, and several conference grants from the Movement Disorders Society and other organizations. She has published numerous papers in leading neurology and medical journals, book chapter in neurology textbooks and encyclopedias, and given over 40 presentations in international conferences.

Dr Aggarwal is actively involved in increasing awareness about neurological disorders among lay people, patients and their families, as well as professionals. She has organised and participated in numerous national and international conferences for education and advocacy of mental health and neurological disorders.

At the Kokilaben Hospital Dr Aggarwal complements her clinical practice with active research in partnership with fellow neurologists and other specialists in India, as well as at the Royal Adelaide Hospital, University of Adelaide, Adelaide, Australia; Westmead Hospital, University of Sydney, Australia; Westphalian Wilhelms-University, Munster, Germany; University of Lubeck, Lubeck, Germany; Harokopio University, Athens, Greece; University College of London, Queen Square, London, UK; and University of California-San Francisco, San Francisco, USA.

Publications

• Sanghvi D, Aggarwal A, Kulkarni B, Singh S, Kothari VM. “Primary CNS vasculitis: Radiopathological correlation", Neurology India, 2019
• Aggarwal A, Bhatt M. “Neurological Wilson disease", In Clinical and translational perspectives on Wilson disease, First edition, Editors: Kerkar N, Roberts EA, Elsevier, 2018
• Aggarwal A, Bhatt M. “Advances in treatment of Wilson disease", Tremor and Other Hyperkinetic Movements, 8, 2018
• Aggarwal A, Thompson PD. Belly Dancer's Dyskinesia", In Reference Module in Neuroscience and Biobehavioral Psychology, Elsevier, 2017
• Aggarwal A, Bhatt M. Wilson Disease Update", In Understanding Parkinsonism: The Clinical Perspective, Editors: Batla A, Vibha D, Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, pp. 289-302, 2017
• Chandhok G, Horvath J, Aggarwal A, Bhatt M, Zibert A, Schmidt HH Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines", World J Gastroenterol, vol. 22(16), pp. 4109-19,2016
• Kapoor H, Wagh H, Tapiawala S, Aggarwal A. Anesthetic management of a known case of serotonin syndrome undergoing renal transplant", J Anaesthesiol Clin Pharmacol, vol. 32(3), pp. 399-400, 2016
• Aggarwal A, Bhatt M, Hyperkinetic movement disorders", In Neurological Practice: An Indian perspective, Second edition, Editors: Khadlikar S, Wadia NH. Elsevier, pp. 241{259, 2015
• Aggarwal A, Bhatt M. The pragmatic treatment of Wilson's disease", Movement Disorders Clinical Practice, vol. 1(1), pp. 14{23, April 2014
• Aggarwal A, Bhatt M, "Neurologic Aspects of Gastrointestinal / HepatoBiliary Diseases: Commonly used gastrointestinal drugs", In Neurological Aspects of Systemic Disease, Volume 120, Editors: Biller J and Ferro JM. Handbook of Clinical Neurology Series, Third Series Editor: Aminoff MJ, Boller F, Swaab DF, Elsevier, vol. 100, pp.633-643,2014
• Aggarwal A, Bhatt, "Hyperkinetic movement disorders & Wilson disease', Neurological Practice: An Indian perspective, Edition 2, Editors: Khadilkar S, Wadia, NH, Elsevier, 2014
• Aggarwal A, Fung V, Thompson P. Hyperkinetic Movement Disorders. In Hankey's Clinical Neurology, Second Edition. Editors: Gorelick P, Testai F, Hankey G, Wardlaw JM. CRC Press, 2014
• Aggarwal A, Bhatt M, "Wilson Disease: an update", In Metals Related Neurodegenerative Diseases, International Reviews of Neurobiology, Editors: Bhatia KP and Scheinder SA, Elsevier, 2013
• Aggarwal A, Thompson PD, "Unusual focal dyskinesias", In Hyperkinetic Movement Disorders, Volume 100 (3rd series), Editors: W.J. Weiner and E. Tolosa. Handbook of Clinical Neurology Series, Third Series Editors:Aminoff MJ, Boller F, Swaab DF, Elsevier B.V., pp.617-628, 2011.
• Aggarwal A, Bhatt M, "Neurologic Aspects of Gastrointestinal / HepatoBiliary Diseases: Commonly used gastrointestinal drugs", In Neurological Aspects of Systemic Disease, Volume 1, Editors: Biller J and Ferro JM. Handbook of Clinical Neurology Series, Third Series Editor: Aminoff MJ, Boller F, Swaab DF, Elsevier B.V., 2011
• Aggarwal A, Geschwind MD "Rapidly progressive dementias", In Reviews in Neurology Editors: Khadilkar S, Singh G Indian Academy of Neurology, pp. 307-28, 2011
• Aggarwal A, Thompson PD. Belly Dancers Dyskinesias. In Encyclopedia of Movement Disorders, vol. 1. Editors: Kompoliti K, Verhagen Metman L. Oxford Academic Press, pp. 127-128, 2010

Professional Memberships

• American Academy of Neurology
• Bombay Neurosciences Association
• Cognitive Neurology Section of Indian Academy of Neurology (Founding member)
• Diplomate of National Board, New Delhi, India
• Indian Academy of Neurology
• Indian Stroke Association
• International Child Neurology Association
• International Parkinson and Movement Disorder Society
• Maharashtra Association of Neurology
• Medical Council of Maharashtra
• Movement Disorders Section of Indian Academy of Neurology
• Neurorehabilitation section of the Indian Academy of Neurology
• Parkinson's Disease Foundation of India
• Royal College of Physicians, London, UK
• Neurological Society of India